diff --git a/ext/node/polyfills/_next_tick.ts b/ext/node/polyfills/_next_tick.ts
index 62470c564e..af306a29c8 100644
--- a/ext/node/polyfills/_next_tick.ts
+++ b/ext/node/polyfills/_next_tick.ts
@@ -62,6 +62,8 @@ export function processTicksAndRejections() {
               callback(...args);
           }
         }
+      } catch (e) {
+        reportError(e);
       } finally {
         // FIXME(bartlomieju): Deno currently doesn't support async hooks
         // if (destroyHooksExist())
diff --git a/tests/integration/node_unit_tests.rs b/tests/integration/node_unit_tests.rs
index d66db5a40e..40bd7b2fbb 100644
--- a/tests/integration/node_unit_tests.rs
+++ b/tests/integration/node_unit_tests.rs
@@ -212,3 +212,7 @@ itest!(unhandled_rejection_web_process {
   envs: env_vars_for_npm_tests(),
   http_server: true,
 });
+
+// !!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
+// The itest macro is deprecated. Please move your new test to ~/tests/specs.
+// !!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
diff --git a/tests/node_compat/config.jsonc b/tests/node_compat/config.jsonc
index 75f463342e..a99a427900 100644
--- a/tests/node_compat/config.jsonc
+++ b/tests/node_compat/config.jsonc
@@ -43,9 +43,6 @@
       // TODO(littledivy): windows ipc streams not yet implemented
       "test-child-process-fork-ref.js",
       "test-child-process-fork-ref2.js",
-      // TODO(bartlomieju): this test is very flaky on CI
-      // https://github.com/denoland/deno/issues/25855
-      // "test-child-process-ipc-next-tick.js",
       "test-child-process-ipc.js",
       "test-child-process-spawnsync-env.js",
       "test-child-process-stdio-inherit.js",
@@ -240,6 +237,7 @@
       "test-child-process-execfilesync-maxbuf.js",
       "test-child-process-execsync-maxbuf.js",
       "test-child-process-flush-stdio.js",
+      "test-child-process-ipc-next-tick.js",
       "test-child-process-kill.js",
       "test-child-process-set-blocking.js",
       "test-child-process-spawn-args.js",
diff --git a/tests/node_compat/runner/TODO.md b/tests/node_compat/runner/TODO.md
index 11b5d28053..35a67e72d2 100644
--- a/tests/node_compat/runner/TODO.md
+++ b/tests/node_compat/runner/TODO.md
@@ -280,7 +280,6 @@ NOTE: This file should not be manually edited. Please edit `tests/node_compat/co
 - [parallel/test-child-process-fork3.js](https://github.com/nodejs/node/tree/v18.12.1/test/parallel/test-child-process-fork3.js)
 - [parallel/test-child-process-http-socket-leak.js](https://github.com/nodejs/node/tree/v18.12.1/test/parallel/test-child-process-http-socket-leak.js)
 - [parallel/test-child-process-internal.js](https://github.com/nodejs/node/tree/v18.12.1/test/parallel/test-child-process-internal.js)
-- [parallel/test-child-process-ipc-next-tick.js](https://github.com/nodejs/node/tree/v18.12.1/test/parallel/test-child-process-ipc-next-tick.js)
 - [parallel/test-child-process-ipc.js](https://github.com/nodejs/node/tree/v18.12.1/test/parallel/test-child-process-ipc.js)
 - [parallel/test-child-process-no-deprecation.js](https://github.com/nodejs/node/tree/v18.12.1/test/parallel/test-child-process-no-deprecation.js)
 - [parallel/test-child-process-pipe-dataflow.js](https://github.com/nodejs/node/tree/v18.12.1/test/parallel/test-child-process-pipe-dataflow.js)
diff --git a/tests/node_compat/test/parallel/test-child-process-ipc-next-tick.js b/tests/node_compat/test/parallel/test-child-process-ipc-next-tick.js
new file mode 100644
index 0000000000..f511d25004
--- /dev/null
+++ b/tests/node_compat/test/parallel/test-child-process-ipc-next-tick.js
@@ -0,0 +1,46 @@
+// deno-fmt-ignore-file
+// deno-lint-ignore-file
+
+// Copyright Joyent and Node contributors. All rights reserved. MIT license.
+// Taken from Node 18.12.1
+// This file is automatically generated by `tests/node_compat/runner/setup.ts`. Do not modify this file manually.
+
+'use strict';
+const common = require('../common');
+const assert = require('assert');
+const cp = require('child_process');
+const NUM_MESSAGES = 10;
+const values = [];
+
+for (let i = 0; i < NUM_MESSAGES; ++i) {
+  values[i] = i;
+}
+
+if (process.argv[2] === 'child') {
+  const received = values.map(() => { return false; });
+
+  process.on('uncaughtException', common.mustCall((err) => {
+    received[err] = true;
+    const done = received.every((element) => { return element === true; });
+
+    if (done)
+      process.disconnect();
+  }, NUM_MESSAGES));
+
+  process.on('message', (msg) => {
+    // If messages are handled synchronously, throwing should break the IPC
+    // message processing.
+    throw msg;
+  });
+
+  process.send('ready');
+} else {
+  const child = cp.fork(__filename, ['child']);
+
+  child.on('message', common.mustCall((msg) => {
+    assert.strictEqual(msg, 'ready');
+    values.forEach((value) => {
+      child.send(value);
+    });
+  }));
+}
diff --git a/tests/specs/node/next_tick_uncaught_exception/__test__.jsonc b/tests/specs/node/next_tick_uncaught_exception/__test__.jsonc
new file mode 100644
index 0000000000..5517e693d6
--- /dev/null
+++ b/tests/specs/node/next_tick_uncaught_exception/__test__.jsonc
@@ -0,0 +1,4 @@
+{
+  "args": "run main.ts",
+  "output": "main.out"
+}
diff --git a/tests/specs/node/next_tick_uncaught_exception/main.out b/tests/specs/node/next_tick_uncaught_exception/main.out
new file mode 100644
index 0000000000..45b756515b
--- /dev/null
+++ b/tests/specs/node/next_tick_uncaught_exception/main.out
@@ -0,0 +1,2 @@
+caught Error: thrown from next tick
+    at file:///[WILDCARD]/specs/node/next_tick_uncaught_exception/main.ts:4:15
diff --git a/tests/specs/node/next_tick_uncaught_exception/main.ts b/tests/specs/node/next_tick_uncaught_exception/main.ts
new file mode 100644
index 0000000000..2679d3d54b
--- /dev/null
+++ b/tests/specs/node/next_tick_uncaught_exception/main.ts
@@ -0,0 +1,13 @@
+import process from "node:process";
+import { strictEqual } from "node:assert";
+
+const error = new Error("thrown from next tick");
+
+process.on("uncaughtException", (caught) => {
+  strictEqual(caught, error);
+  console.log("caught", caught);
+});
+
+process.nextTick(() => {
+  throw error;
+});