diff --git a/cli/args/config_file.rs b/cli/args/config_file.rs
index 16e11a5a81..904efdff8d 100644
--- a/cli/args/config_file.rs
+++ b/cli/args/config_file.rs
@@ -429,6 +429,28 @@ pub struct TestConfig {
   pub files: FilesConfig,
 }
 
+#[derive(Clone, Debug, Default, Deserialize)]
+#[serde(default, deny_unknown_fields)]
+struct SerializedBenchConfig {
+  pub files: SerializedFilesConfig,
+}
+
+impl SerializedBenchConfig {
+  pub fn into_resolved(
+    self,
+    config_file_specifier: &ModuleSpecifier,
+  ) -> Result<BenchConfig, AnyError> {
+    Ok(BenchConfig {
+      files: self.files.into_resolved(config_file_specifier)?,
+    })
+  }
+}
+
+#[derive(Clone, Debug, Default)]
+pub struct BenchConfig {
+  pub files: FilesConfig,
+}
+
 #[derive(Clone, Debug, Deserialize)]
 #[serde(untagged)]
 pub enum LockConfig {
@@ -445,6 +467,7 @@ pub struct ConfigFileJson {
   pub fmt: Option<Value>,
   pub tasks: Option<Value>,
   pub test: Option<Value>,
+  pub bench: Option<Value>,
   pub lock: Option<Value>,
 }
 
@@ -653,9 +676,19 @@ impl ConfigFile {
 
   pub fn to_test_config(&self) -> Result<Option<TestConfig>, AnyError> {
     if let Some(config) = self.json.test.clone() {
-      let lint_config: SerializedTestConfig = serde_json::from_value(config)
+      let test_config: SerializedTestConfig = serde_json::from_value(config)
         .context("Failed to parse \"test\" configuration")?;
-      Ok(Some(lint_config.into_resolved(&self.specifier)?))
+      Ok(Some(test_config.into_resolved(&self.specifier)?))
+    } else {
+      Ok(None)
+    }
+  }
+
+  pub fn to_bench_config(&self) -> Result<Option<BenchConfig>, AnyError> {
+    if let Some(config) = self.json.bench.clone() {
+      let bench_config: SerializedBenchConfig = serde_json::from_value(config)
+        .context("Failed to parse \"bench\" configuration")?;
+      Ok(Some(bench_config.into_resolved(&self.specifier)?))
     } else {
       Ok(None)
     }
diff --git a/cli/args/mod.rs b/cli/args/mod.rs
index 3f3f53d183..ebe71c7fab 100644
--- a/cli/args/mod.rs
+++ b/cli/args/mod.rs
@@ -6,6 +6,7 @@ mod lockfile;
 
 mod flags_allow_net;
 
+pub use config_file::BenchConfig;
 pub use config_file::CompilerOptions;
 pub use config_file::ConfigFile;
 pub use config_file::EmitConfigOptions;
@@ -401,6 +402,14 @@ impl CliOptions {
     }
   }
 
+  pub fn to_bench_config(&self) -> Result<Option<BenchConfig>, AnyError> {
+    if let Some(config_file) = &self.maybe_config_file {
+      config_file.to_bench_config()
+    } else {
+      Ok(None)
+    }
+  }
+
   pub fn to_fmt_config(&self) -> Result<Option<FmtConfig>, AnyError> {
     if let Some(config) = &self.maybe_config_file {
       config.to_fmt_config()
diff --git a/cli/schemas/config-file.v1.json b/cli/schemas/config-file.v1.json
index 7f6dcb4e3c..67650309ea 100644
--- a/cli/schemas/config-file.v1.json
+++ b/cli/schemas/config-file.v1.json
@@ -356,6 +356,31 @@
         }
       }
     },
+    "bench": {
+      "description": "Configuration for deno bench",
+      "type": "object",
+      "properties": {
+        "files": {
+          "type": "object",
+          "properties": {
+            "include": {
+              "type": "array",
+              "description": "List of files or directories that will be searched for benchmarks.",
+              "items": {
+                "type": "string"
+              }
+            },
+            "exclude": {
+              "type": "array",
+              "description": "List of files or directories that will not be searched for benchmarks.",
+              "items": {
+                "type": "string"
+              }
+            }
+          }
+        }
+      }
+    },
     "lock": {
       "description": "Whether to use a lock file or the path to use for the lock file. Can be overridden by CLI arguments.",
       "type": ["string", "boolean"],
diff --git a/cli/tests/bench_tests.rs b/cli/tests/bench_tests.rs
index 77c1e2a7ef..24d2a4fe92 100644
--- a/cli/tests/bench_tests.rs
+++ b/cli/tests/bench_tests.rs
@@ -165,6 +165,24 @@ mod bench {
     exit_code: 1,
   });
 
+  itest!(bench_with_config {
+    args: "bench --config bench/collect/deno.jsonc bench/collect",
+    exit_code: 0,
+    output: "bench/collect.out",
+  });
+
+  itest!(bench_with_config2 {
+    args: "bench --config bench/collect/deno2.jsonc bench/collect",
+    exit_code: 0,
+    output: "bench/collect2.out",
+  });
+
+  itest!(bench_with_malformed_config {
+    args: "bench --config bench/collect/deno.malformed.jsonc",
+    exit_code: 1,
+    output: "bench/collect_with_malformed_config.out",
+  });
+
   #[test]
   fn recursive_permissions_pledge() {
     let output = util::deno_cmd()
diff --git a/cli/tests/testdata/bench/collect.out b/cli/tests/testdata/bench/collect.out
index 18b27f8b93..a7adc2b588 100644
--- a/cli/tests/testdata/bench/collect.out
+++ b/cli/tests/testdata/bench/collect.out
@@ -1,7 +1,17 @@
 Check [WILDCARD]/bench/collect/bench.ts
+Check [WILDCARD]/bench/collect/include/2_bench.ts
+Check [WILDCARD]/bench/collect/include/bench.ts
 cpu: [WILDCARD]
 runtime: deno [WILDCARD] ([WILDCARD])
 
 [WILDCARD]/bench/collect/bench.ts
 benchmark      time (avg)             (min … max)       p75       p99      p995
 ------------------------------------------------- -----------------------------
+
+[WILDCARD]/bench/collect/include/2_bench.ts
+benchmark      time (avg)             (min … max)       p75       p99      p995
+------------------------------------------------- -----------------------------
+
+[WILDCARD]/bench/collect/include/bench.ts
+benchmark      time (avg)             (min … max)       p75       p99      p995
+------------------------------------------------- -----------------------------
diff --git a/cli/tests/testdata/bench/collect/deno.jsonc b/cli/tests/testdata/bench/collect/deno.jsonc
new file mode 100644
index 0000000000..f88d137781
--- /dev/null
+++ b/cli/tests/testdata/bench/collect/deno.jsonc
@@ -0,0 +1,7 @@
+{
+    "bench": {
+      "files": {
+        "exclude": ["./ignore"]
+      }
+    }
+}
diff --git a/cli/tests/testdata/bench/collect/deno.malformed.jsonc b/cli/tests/testdata/bench/collect/deno.malformed.jsonc
new file mode 100644
index 0000000000..02744bc111
--- /dev/null
+++ b/cli/tests/testdata/bench/collect/deno.malformed.jsonc
@@ -0,0 +1,5 @@
+{
+    "bench": {
+      "dont_know_this_field": {}
+    }
+}
diff --git a/cli/tests/testdata/bench/collect/deno2.jsonc b/cli/tests/testdata/bench/collect/deno2.jsonc
new file mode 100644
index 0000000000..f24da50491
--- /dev/null
+++ b/cli/tests/testdata/bench/collect/deno2.jsonc
@@ -0,0 +1,8 @@
+{
+    "bench": {
+      "files": {
+        "include": ["./include/"],
+        "exclude": ["./ignore", "./include/2_bench.ts"]
+      }
+    }
+}
diff --git a/cli/tests/testdata/bench/collect/include/2_bench.ts b/cli/tests/testdata/bench/collect/include/2_bench.ts
new file mode 100644
index 0000000000..e69de29bb2
diff --git a/cli/tests/testdata/bench/collect/include/bench.ts b/cli/tests/testdata/bench/collect/include/bench.ts
new file mode 100644
index 0000000000..e69de29bb2
diff --git a/cli/tests/testdata/bench/collect2.out b/cli/tests/testdata/bench/collect2.out
new file mode 100644
index 0000000000..e5bb0f1c5d
--- /dev/null
+++ b/cli/tests/testdata/bench/collect2.out
@@ -0,0 +1,12 @@
+Check [WILDCARD]/bench/collect/bench.ts
+Check [WILDCARD]/bench/collect/include/bench.ts
+cpu: [WILDCARD]
+runtime: deno [WILDCARD] ([WILDCARD])
+
+[WILDCARD]/bench/collect/bench.ts
+benchmark      time (avg)             (min … max)       p75       p99      p995
+------------------------------------------------- -----------------------------
+
+[WILDCARD]/bench/collect/include/bench.ts
+benchmark      time (avg)             (min … max)       p75       p99      p995
+------------------------------------------------- -----------------------------
diff --git a/cli/tests/testdata/bench/collect_with_malformed_config.out b/cli/tests/testdata/bench/collect_with_malformed_config.out
new file mode 100644
index 0000000000..10e64707ca
--- /dev/null
+++ b/cli/tests/testdata/bench/collect_with_malformed_config.out
@@ -0,0 +1,4 @@
+error: Failed to parse "bench" configuration
+
+Caused by:
+    unknown field `dont_know_this_field`, expected `files`
diff --git a/cli/tools/bench.rs b/cli/tools/bench.rs
index eeda3ea1a2..2bebe124b1 100644
--- a/cli/tools/bench.rs
+++ b/cli/tools/bench.rs
@@ -1,5 +1,6 @@
 // Copyright 2018-2022 the Deno authors. All rights reserved. MIT license.
 
+use crate::args::BenchConfig;
 use crate::args::BenchFlags;
 use crate::args::Flags;
 use crate::args::TypeCheckMode;
@@ -14,6 +15,7 @@ use crate::util::file_watcher;
 use crate::util::file_watcher::ResolutionResult;
 use crate::util::fs::collect_specifiers;
 use crate::util::path::is_supported_ext;
+use crate::util::path::specifier_to_file_path;
 use crate::worker::create_main_worker_for_test_or_bench;
 
 use deno_core::error::generic_error;
@@ -490,9 +492,13 @@ pub async fn run_benchmarks(
   let ps = ProcState::build(flags).await?;
   let permissions =
     Permissions::from_options(&ps.options.permissions_options())?;
+
+  let selection =
+    collect_include_ignore(&bench_flags, ps.options.to_bench_config()?);
+
   let specifiers = collect_specifiers(
-    bench_flags.include.unwrap_or_else(|| vec![".".to_string()]),
-    &bench_flags.ignore.clone(),
+    selection.include,
+    &selection.ignore,
     is_supported_bench_path,
   )?;
 
@@ -524,9 +530,11 @@ pub async fn run_benchmarks_with_watch(
   let permissions =
     Permissions::from_options(&ps.options.permissions_options())?;
 
-  let include = bench_flags.include.unwrap_or_else(|| vec![".".to_string()]);
-  let ignore = bench_flags.ignore.clone();
-  let paths_to_watch: Vec<_> = include.iter().map(PathBuf::from).collect();
+  let selection =
+    collect_include_ignore(&bench_flags, ps.options.to_bench_config()?);
+
+  let paths_to_watch: Vec<_> =
+    selection.include.iter().map(PathBuf::from).collect();
   let no_check = ps.options.type_check_mode() == TypeCheckMode::None;
 
   let resolver = |changed: Option<Vec<PathBuf>>| {
@@ -534,8 +542,8 @@ pub async fn run_benchmarks_with_watch(
     let paths_to_watch_clone = paths_to_watch.clone();
 
     let files_changed = changed.is_some();
-    let include = include.clone();
-    let ignore = ignore.clone();
+    let include = selection.include.clone();
+    let ignore = selection.ignore.clone();
     let ps = ps.clone();
 
     async move {
@@ -650,8 +658,8 @@ pub async fn run_benchmarks_with_watch(
 
   let operation = |modules_to_reload: Vec<(ModuleSpecifier, ModuleKind)>| {
     let filter = bench_flags.filter.clone();
-    let include = include.clone();
-    let ignore = ignore.clone();
+    let include = selection.include.clone();
+    let ignore = selection.ignore.clone();
     let permissions = permissions.clone();
     let ps = ps.clone();
 
@@ -687,3 +695,42 @@ pub async fn run_benchmarks_with_watch(
 
   Ok(())
 }
+
+struct IncludeIgnoreCollection {
+  include: Vec<String>,
+  ignore: Vec<PathBuf>,
+}
+
+fn collect_include_ignore(
+  bench_flags: &BenchFlags,
+  maybe_bench_config: Option<BenchConfig>,
+) -> IncludeIgnoreCollection {
+  let mut include = bench_flags.include.clone().unwrap_or_default();
+  let mut ignore = bench_flags.ignore.clone();
+
+  if let Some(bench_config) = maybe_bench_config {
+    if include.is_empty() {
+      include = bench_config
+        .files
+        .include
+        .iter()
+        .map(|s| s.to_string())
+        .collect::<Vec<_>>();
+    }
+
+    if ignore.is_empty() {
+      ignore = bench_config
+        .files
+        .exclude
+        .iter()
+        .filter_map(|s| specifier_to_file_path(s).ok())
+        .collect::<Vec<_>>();
+    }
+  }
+
+  if include.is_empty() {
+    include.push(".".to_string());
+  }
+
+  IncludeIgnoreCollection { include, ignore }
+}