diff --git a/tools/wpt.ts b/tools/wpt.ts
index ad30b95b45..b1067655cd 100755
--- a/tools/wpt.ts
+++ b/tools/wpt.ts
@@ -679,6 +679,16 @@ function discoverTestsToRun(
 
           if (expectation === undefined) continue;
 
+          if (typeof expectation === "object") {
+            if (typeof expectation.ignore !== "undefined") {
+              assert(
+                typeof expectation.ignore === "boolean",
+                "test entry's `ignore` key must be a boolean",
+              );
+              if (expectation.ignore === true) continue;
+            }
+          }
+
           assert(
             Array.isArray(expectation) || typeof expectation == "boolean",
             "test entry must not have a folder expectation",
diff --git a/tools/wpt/expectation.json b/tools/wpt/expectation.json
index 8bab051595..b5df6cacf1 100644
--- a/tools/wpt/expectation.json
+++ b/tools/wpt/expectation.json
@@ -1099,71 +1099,9 @@
       ]
     },
     "wrapKey_unwrapKey": {
-      "wrapKey_unwrapKey.https.any.worker.html": [
-        "Can wrap and unwrap ECDH public key keys using spki and AES-CTR",
-        "Can wrap and unwrap ECDH public key keys using spki and AES-CBC",
-        "Can wrap and unwrap ECDSA public key keys using spki and AES-GCM",
-        "Can wrap and unwrap ECDSA public key keys using jwk and AES-GCM",
-        "Can wrap and unwrap ECDSA private key keys using pkcs8 and AES-GCM",
-        "Can wrap and unwrap ECDSA private key keys as non-extractable using pkcs8 and AES-GCM",
-        "Can wrap and unwrap ECDSA private key keys using jwk and AES-GCM",
-        "Can wrap and unwrap ECDSA private key keys as non-extractable using jwk and AES-GCM",
-        "Can unwrap ECDSA private key non-extractable keys using jwk and AES-GCM",
-        "Can wrap and unwrap ECDH public key keys using spki and AES-GCM",
-        "Can wrap and unwrap ECDH public key keys using jwk and AES-GCM",
-        "Can wrap and unwrap ECDH private key keys using pkcs8 and AES-GCM",
-        "Can wrap and unwrap ECDH private key keys as non-extractable using pkcs8 and AES-GCM",
-        "Can wrap and unwrap ECDH private key keys using jwk and AES-GCM",
-        "Can wrap and unwrap ECDH private key keys as non-extractable using jwk and AES-GCM",
-        "Can unwrap ECDH private key non-extractable keys using jwk and AES-GCM",
-        "Can wrap and unwrap HMAC keys using raw and AES-GCM",
-        "Can wrap and unwrap HMAC keys as non-extractable using raw and AES-GCM",
-        "Can wrap and unwrap HMAC keys using jwk and AES-GCM",
-        "Can wrap and unwrap HMAC keys as non-extractable using jwk and AES-GCM",
-        "Can unwrap HMAC non-extractable keys using jwk and AES-GCM",
-        "Can wrap and unwrap AES-CTR keys using raw and AES-GCM",
-        "Can wrap and unwrap AES-CTR keys as non-extractable using raw and AES-GCM",
-        "Can wrap and unwrap AES-CTR keys using jwk and AES-GCM",
-        "Can wrap and unwrap AES-CTR keys as non-extractable using jwk and AES-GCM",
-        "Can unwrap AES-CTR non-extractable keys using jwk and AES-GCM",
-        "Can wrap and unwrap AES-CBC keys using raw and AES-GCM",
-        "Can wrap and unwrap AES-CBC keys as non-extractable using raw and AES-GCM",
-        "Can wrap and unwrap AES-CBC keys using jwk and AES-GCM",
-        "Can wrap and unwrap AES-CBC keys as non-extractable using jwk and AES-GCM",
-        "Can unwrap AES-CBC non-extractable keys using jwk and AES-GCM",
-        "Can wrap and unwrap AES-GCM keys using raw and AES-GCM",
-        "Can wrap and unwrap AES-GCM keys as non-extractable using raw and AES-GCM",
-        "Can wrap and unwrap AES-GCM keys using jwk and AES-GCM",
-        "Can wrap and unwrap AES-GCM keys as non-extractable using jwk and AES-GCM",
-        "Can unwrap AES-GCM non-extractable keys using jwk and AES-GCM",
-        "Can wrap and unwrap AES-KW keys using raw and AES-GCM",
-        "Can wrap and unwrap AES-KW keys as non-extractable using raw and AES-GCM",
-        "Can wrap and unwrap AES-KW keys using jwk and AES-GCM",
-        "Can wrap and unwrap AES-KW keys as non-extractable using jwk and AES-GCM",
-        "Can unwrap AES-KW non-extractable keys using jwk and AES-GCM",
-        "Can wrap and unwrap RSASSA-PKCS1-v1_5 public key keys using spki and AES-GCM",
-        "Can wrap and unwrap RSASSA-PKCS1-v1_5 public key keys using jwk and AES-GCM",
-        "Can wrap and unwrap RSASSA-PKCS1-v1_5 private key keys using pkcs8 and AES-GCM",
-        "Can wrap and unwrap RSASSA-PKCS1-v1_5 private key keys as non-extractable using pkcs8 and AES-GCM",
-        "Can wrap and unwrap RSASSA-PKCS1-v1_5 private key keys using jwk and AES-GCM",
-        "Can wrap and unwrap RSASSA-PKCS1-v1_5 private key keys as non-extractable using jwk and AES-GCM",
-        "Can unwrap RSASSA-PKCS1-v1_5 private key non-extractable keys using jwk and AES-GCM",
-        "Can wrap and unwrap RSA-OAEP public key keys using spki and AES-GCM",
-        "Can wrap and unwrap RSA-OAEP public key keys using jwk and AES-GCM",
-        "Can wrap and unwrap RSA-OAEP private key keys using pkcs8 and AES-GCM",
-        "Can wrap and unwrap RSA-OAEP private key keys as non-extractable using pkcs8 and AES-GCM",
-        "Can wrap and unwrap RSA-OAEP private key keys using jwk and AES-GCM",
-        "Can wrap and unwrap RSA-OAEP private key keys as non-extractable using jwk and AES-GCM",
-        "Can unwrap RSA-OAEP private key non-extractable keys using jwk and AES-GCM",
-        "Can wrap and unwrap RSA-PSS public key keys using spki and AES-GCM",
-        "Can wrap and unwrap RSA-PSS public key keys using jwk and AES-GCM",
-        "Can wrap and unwrap RSA-PSS private key keys using pkcs8 and AES-GCM",
-        "Can wrap and unwrap RSA-PSS private key keys as non-extractable using pkcs8 and AES-GCM",
-        "Can wrap and unwrap RSA-PSS private key keys using jwk and AES-GCM",
-        "Can wrap and unwrap RSA-PSS private key keys as non-extractable using jwk and AES-GCM",
-        "Can unwrap RSA-PSS private key non-extractable keys using jwk and AES-GCM",
-        "Can wrap and unwrap ECDH public key keys using spki and RSA-OAEP"
-      ],
+      "wrapKey_unwrapKey.https.any.worker.html": {
+        "ignore": true
+      },
       "wrapKey_unwrapKey.https.any.html": [
         "Can wrap and unwrap ECDH public key keys using spki and AES-CTR",
         "Can wrap and unwrap ECDH public key keys using spki and AES-CBC",
@@ -3132,7 +3070,9 @@
           "Fetch with POST with ReadableStream containing Blob",
           "Fetch with POST with text body on 421 response should be retried once on new connection."
         ],
-        "response-null-body.any.worker.html": true,
+        "response-null-body.any.worker.html": {
+          "ignore": true
+        },
         "response-url.sub.any.html": true,
         "response-url.sub.any.worker.html": true,
         "scheme-about.any.html": true,