diff --git a/cli/tests/integration/run_tests.rs b/cli/tests/integration/run_tests.rs
index adaa6d49dd..9c60cc7454 100644
--- a/cli/tests/integration/run_tests.rs
+++ b/cli/tests/integration/run_tests.rs
@@ -2738,6 +2738,13 @@ itest!(report_error_handled {
   output: "report_error_handled.ts.out",
 });
 
+// Regression test for https://github.com/denoland/deno/issues/15513.
+itest!(report_error_end_of_program {
+  args: "run --quiet report_error_end_of_program.ts",
+  output: "report_error_end_of_program.ts.out",
+  exit_code: 1,
+});
+
 itest!(spawn_stdout_inherit {
   args: "run --quiet --unstable -A spawn_stdout_inherit.ts",
   output: "spawn_stdout_inherit.ts.out",
diff --git a/cli/tests/testdata/report_error_end_of_program.ts b/cli/tests/testdata/report_error_end_of_program.ts
new file mode 100644
index 0000000000..cd7ce7f9c8
--- /dev/null
+++ b/cli/tests/testdata/report_error_end_of_program.ts
@@ -0,0 +1 @@
+reportError(new Error("foo"));
diff --git a/cli/tests/testdata/report_error_end_of_program.ts.out b/cli/tests/testdata/report_error_end_of_program.ts.out
new file mode 100644
index 0000000000..ecca633893
--- /dev/null
+++ b/cli/tests/testdata/report_error_end_of_program.ts.out
@@ -0,0 +1,4 @@
+error: Uncaught Error: foo
+reportError(new Error("foo"));
+            ^
+    at [WILDCARD]/report_error_end_of_program.ts:1:13
diff --git a/core/runtime.rs b/core/runtime.rs
index def38e1eb5..68c3ab0023 100644
--- a/core/runtime.rs
+++ b/core/runtime.rs
@@ -1156,14 +1156,14 @@ pub(crate) fn exception_to_err_result<'s, T>(
 ) -> Result<T, Error> {
   let state_rc = JsRuntime::state(scope);
 
-  let is_terminating_exception = scope.is_execution_terminating();
+  let was_terminating_execution = scope.is_execution_terminating();
+  // If TerminateExecution was called, cancel isolate termination so that the
+  // exception can be created. Note that `scope.is_execution_terminating()` may
+  // have returned false if TerminateExecution was indeed called but there was
+  // no JS to execute after the call.
+  scope.cancel_terminate_execution();
   let mut exception = exception;
-
-  if is_terminating_exception {
-    // TerminateExecution was called. Cancel isolate termination so that the
-    // exception can be created..
-    scope.cancel_terminate_execution();
-
+  {
     // If the termination is the result of a `Deno.core.terminate` call, we want
     // to use the exception that was passed to it rather than the exception that
     // was passed to this function.
@@ -1191,8 +1191,8 @@ pub(crate) fn exception_to_err_result<'s, T>(
     );
   }
 
-  if is_terminating_exception {
-    // Re-enable exception termination.
+  if was_terminating_execution {
+    // Resume exception termination.
     scope.terminate_execution();
   }
 
@@ -3448,7 +3448,7 @@ assertEquals(1, notify_return_value);
         Deno.core.ops.op_set_promise_reject_callback((type, promise, reason) => {
           Deno.core.ops.op_promise_reject();
         });
-        
+
         throw new Error('top level throw');
         "#;